The Growing Concern of Pain & Inflammation

The average age of the population has been rapidly increasing.

This trend is projected to continue and by 2050, approximately 22% of the global population, or two billion individuals, will be over 60 years old.

In the United States, census data indicates that the number of individuals aged 65 years or older is estimated to reach 83.7 million by 2050, which is almost double the figure from 2012, largely due to the baby boomer generation turning 65 since 2011.

As this demographic grows, the number of individuals with age-related conditions is also expected to increase. Presently, 54 million adults in the US are living with doctor-diagnosed arthritis, and this number is anticipated to increase to 78 million by 2040.

It is projected that globally, 130 million individuals will suffer from joint pain and inflammatory issues like arthritis by 2050.

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Who Is Most Affected by Joint Pain?

Women
Almost 60% of American adults with arthritis are Women. Severe joint pain is higher among women (29.2%) than men (22.7%).

Working age adults
Almost 2/3 of adults with arthritis are 18-64 years of age. Severe joint pain is highest among adults aged 45-64 (30.7%) compared to seniors (24.3%).

Gym Goers
Middle-aged adults who engage in high-impact physical activity are at increased risk for knee damage. 56% of active adults have sustained an exercise-related injury.

People with chronic conditions
49% of adults with heart disease have arthritis and 47% of adults with diabetes have arthritis. Painful joints can be caused by arthritis, bursitis, gout, strains, sprains, and other injuries.

Overweight and obese
Obese adults have about 2x the rate of arthritis (31%) compared to under/normal weight adults (16%). Overweight people have 4-5x the risk of knee osteoarthritis.

Everyone
About 1/3 of adults report having joint pain within the last 30 days The most common form of joint pain is knee pain, followed by shoulder and hip pain.
About 1/3 of adults report having joint pain within the last 30 days The most common form of joint pain is knee pain, followed by shoulder and hip pain.

The Limitations of Popular Joint Health Supplements

There are several remedies available for joint pain and stiffness, but each of them has its own set of limitations.

Pharmaceuticals, such as nonsteroidal anti-inflammatory drugs (NSAIDS), can have severe side effects if used for extended periods. Collagen necessitates high doses, which can be cumbersome, and there is mixed scientific evidence supporting glucosamine's effectiveness. Moreover, harvesting boswellia poses sustainability issues.

Turmeric, with its most popular and extensively studied component, curcumin, is the primary botanical ingredient for joint health.

However, curcumin's extremely low bioavailability presents a significant challenge for consumers due to its insolubility in the gastrointestinal tract's aqueous environment, owing to its polarity and poor dissolution rate. As a result, it is not well absorbed by the system.

Furthermore, curcumin is generally extracted using harsh industrial solvents, which can be a concern for those seeking clean-label products. Consumers are in search of safe, natural, effective, and convenient joint health solutions. Could the answer be a new type of turmeric extract?

Turmeric: The Golden Spice

Turmeric is a remarkable root with a rich history of use in India spanning almost 4,000 years. Its versatility is truly awe-inspiring, with applications in culinary, cosmetic, and medicinal domains.

The ground, dried turmeric root not only imparts a vibrant golden hue and a distinct flavor to curries, but the fresh root also adds depth to stews and soups. Turmeric's cosmetic benefits are no less impressive, as it is commonly used topically to impart a radiant, golden glow to the skin.

In Ayurvedic medicine, turmeric is held in high esteem for its efficacy in treating various digestive disorders, including dyspepsia, acidity, indigestion, flatulence, and ulcers. Moreover, turmeric is a potent anti-inflammatory agent and pain reliever.

All in all, this ancient root is a true powerhouse of wellness and vitality.

Water-Soluble and Oil-Soluble Components of Turmeric

Ayurvedic preparations of turmeric have a long and distinguished history, with both oil-based and aqueous formulations being employed.

Sneha, which incorporates turmeric with ghee, and Kashaya, which blends turmeric with water, exemplify this diverse range of preparations. Notably, both the oil and water-soluble portions of turmeric have been utilized in traditional Ayurvedic medicine.

However, despite turmeric's broad usage, the bulk of scientific research on turmeric-based products has centered on only a select few components. These include whole turmeric powder, volatile oil portions of turmeric, and isolated curcuminoid extracts, with a particular focus on curcumin.

Regrettably, the majority of the remaining water-soluble constituents of turmeric have received scant attention and remain largely unexplored for their therapeutic potential. This raises a compelling question - what valuable bioactive compounds have we been overlooking?

After years and years of research by a team of herbalists and scientists, a company called Natural Remedies discovered that turmeric also contains a special class of water-soluble polysaccharides that are potent, promising, and bioactive. They named them Turmerosaccharides™.

The power of this new form of turmeric

Research has highlighted the potential benefits of Turmerosaccharides™, a class of water-soluble constituents in turmeric, in supporting joint health and function.

These bioactive compounds, along with the fat-soluble curcumin and turmerones, have been shown to alleviate pain and reduce inflammation. Notably, a study found that an oil-free aqueous extract of turmeric was as effective as curcuminoids and turmerones in combating acute and chronic inflammation.

Moreover, several well-controlled human clinical trials have confirmed the efficacy of Turmerosaccharides™ in reducing joint tenderness and improving physical function. What's more, Turmerosaccharides™ do not require any additional processing to be bioavailable, in contrast to curcuminoids.

These compounds are already present in a readily absorbed, retained, and utilized form. Based on positive results from pre-clinical studies, Natural Remedies developed a unique turmeric extract called Turmacin®, which was then subjected to clinical testing.

An innovative ingredient in the crowded turmeric field, Turmacin® is the first standardized turmeric product to focus on the much ignored water-soluble components of turmeric — Turmerosaccharides™.

Benefits of Turmacin^®

- Is a water-extracted turmeric product, completely untouched by solvents.

- Does not contain any curcuminoids and is naturally bioavailable because of its water solubility.

- Has powerful anti-inflammatory activity and reduces pain severity by 50% in 3 hours, according to pre-clinical research.

- Reduces joint tenderness and supports physical function of the joints, as demonstrated by four randomized, placebo-controlled human clinical trials.

- Is safe for long-term use, as shown in both pre-clinical animal as well as human safety studies.

- Can be incorporated into a wide variety of formulations, both solid and liquid.

Clinical Evidence for Turmacin^®:

Study 1: Safety and efficacy of Curcumin longa extract in the treatment of painful knee osteoarthritis: a randomized placebo-controlled trial

Study Design: Researchers divided study participants into four groups. One group took 500 mg of Turmacin® twice a day, a second group took glucosamine (1.5 grams a day), a third group took both, and a fourth group took placebo for 42 days.

Results: Turmacin® achieved statistically significant effects in all three scales.

Key Takeaway: This study shows that Turmacin® is effective for symptom relief among people with osteoarthritis.

Study 2: Effect of Turmacin® supplementation on joint discomfort and functional outcome among healthy participants – a randomized placebo-controlled trial

Participants: 90 healthy volunteers
Study type: Double-blind, placebo-controlled, randomized clinical trial
Study Design: Study volunteers were divided into three groups. The first group took 500 mg of Turmacin® daily, the second group took 1,000 mg daily, and the third group took placebo for 12 weeks.

Results:
• Turmacin® significantly decreased joint pain by day 5.
• Turmacin® increased time to onset of pain during exercise.
• Turmacin® preserved muscle strength during periods of physical inactivity.
• Turmacin® improved joint mobility.

Key Takeaway: Previous research has shown that Turmacin® is effective for symptom relief among people with osteoarthritis. This study indicates that Turmacin® also has joint and muscle health benefits for healthy and physically active people.

Study 3: The Effect of Turmacin® on Inflammation and Pain Severity

Preclinical animal studies show Turmacin® significantly reduces joint pain. In one of these studies, pain (as measured by how much weight the animals bore on their injured hind legs) was reduced by 50% in 3 hours. The effect lasted for 24 hours.

As in humans, Turmacin® was more effective at decreasing joint pain than glucosamine. Turmacin® also reduced inflammation compared to untreated controls. In vitro research provides additional evidence for the ability of Turmacin® to suppress inflammation.

Health benefits of Turmacin:

Adults with symptoms of osteoarthritis
• Decreases self-reported pain and stiffness
• Decreases practitioner-assessed joint tenderness, swelling, crepitation, and limitation of movement
• Reduces the use of NSAIDs and other OTC pain medications
Healthy, physically active adults
• Decreases exercise-induced joint pain
• Increases joint mobility
• Increases time to onset of pain during exercise
• Preserves muscle strength during periods of inactivity and supports joint range of motion
• Improves muscle tension

The tastiest source of turmacin:

Looking for a conveinent and effective way to manage pain and inflammation?

Try happy being healthy. This tea delivers 250mg of Turmacin, plus other antioxidants & polyphenols like pterostilbene, elderberry, vitamin D, and EGCG.

Works cited:
World population projected to reach 9.8 billion in 2050, and 11.2 billion in 2100. United Nations Department of Economic and Social Affairs. Jun 21, 2017.
United States Census Bureau. Fueled by Aging Baby Boomers, Nation’s Older Population to Nearly Double in the Next 20 Years, Census Bureau Reports. May 6, 2014.
Arthritis-related statistics. Centers for Disease Control and Prevention. July 18, 2018. Centers for Disease Control and Prevention. July 18, 2018.
The truth about arthritis. Arthritis Society. Joint pain and arthritis. Centers for Disease Control and Prevention. Sep 19, 2018.
Hootman JM, Helmick CG, Brady TJ. A public health approach to addressing arthritis in older adults: The most common cause of disability. Amer J Public Health. Mar 2012;102(3):426-33. Centers for Disease Control and Prevention. Sep 19, 2018.
Too Much Exercise May Pose Arthritis Risk. WebMD. Arthritis and Osteoporosis. National Center for Biotechnology Information. Arthritis-related statistics. Centers for Disease Control and Prevention. July 18, 2018.
Role of body weight in osteoarthritis. Johns Hopkins Arthritis Center. Arthritis cases surge. AARP. Mar 8, 2017. AARP. Mar 8, 2017.
Joint Pain. WebMD. Reviewed by David Zelman, MD on Jun 17, 2019.
Global bone and joint health ingredients market—growth, trends, and forecast (2019-2024). Mordor Intelligence.
Turmeric: a herbal and traditional medicine. Scholars Research Library. 2009;1(2):86-108. Turmeric: an overview. Science Direct. 2019.
2019 Ingredient Trends to Watch for Food, Drinks, and Dietary Supplements: Turmeric. Nutritional Outlook. Feb 8, 2019.
2019 Ingredient Trends to Watch for Food, Drinks, and Dietary Supplements: Turmeric. Nutritional Outlook. Feb 8, 2019.
Turmeric Goes Mainstream at Expo West: demonstrating the herb’s dominance, Natural Products Expo West was abundant with turmeric snacks, drinks, supplements & more. Nutraceuticals World. Mar 23, 2018.
MacKeen, Dawn. What Are the Benefits of Turmeric? The New York Times. Oct. 16, 2019. Comparative evaluation of anti-inflammatory activity of curcuminoids, tumerones, and aqueous extracts of Curcuma longa. Adv Pharmacol Sci. 2013;2013:805756. doi: 10.1155/2013/805756.
Madhu K, Chandra K, Sali MJ. Safety and efficacy of Curcumin longa extract in the treatment of painful knee osteoarthritis: a randomized placebo-controlled trial. Inflammopharmacol. 2013;21:129-136.
Murugan S, et al. Antiarthritic effect of polar extract of Curcuma longa on monosodium iodoacetate induced osteoarthritis in rats. Antiinflamm Antiallergy Agents Med Chem. 2017;16(3):193-202.

The Mose Effective Form of Turmeric for Joint Pain & Bone Health